单壶制粒已在制药行业中使用数十年。单壶造粒在一个工艺碗中将混合,高剪切湿造粒和干燥(真空干燥,载气干燥或微波干燥)结合在一起。磅。Bohle的单壶造粒产品包括用于小型生产卷的研发系统以及生产尺度系统。用L.B造粒。Bohle单壶造粒机VMA产品系列包括具有搅拌器和斩波装置的经典单壶造粒机和顶级驱动。两个搅拌器产生剪切动作并松开产品。这有助于防止丛集并确保所得的颗粒是最佳质量。符合GMP标准的工艺碗,具有双壳是VMA的核心。主要聚集体集成在造粒罐(顶部驱动器)的盖子中。 The process bowl is emptied through a cone-shaped sieve (BTS 200) via the floor outlet into a container (IBC). Recipe-controlled cleaning is carried out automatically. The VMA produces batch sizes from 20 to 960 litres and can be installed in explosive atmospheres. Benefits of the Single Pot Granulator Safe production inside a closed bowl in a vacuum - High mixing and granulation efficiency (even for low doses of active agents at < 1%) - Low energy consumption: Drying at low temperatures - Easy operation and cleaning, as well as quick product changes - Efficient solvent recovery through cooling water - Small footprint